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Obesity and Weight Loss
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome – (12-10-01)
James Bogash
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome
This article takes a new look at an old problem–visceral abdominal fat is the fat that creates the increased disease risk seen with obesity. Although excess cortisol has been implicated in a major causative factor leading to harmful changes in these cells, there are no studies that have been able to identify elevated levels in obesity. This study (done with mice) confirms the possibility that visceral adipose tissues have increased levels of intracellular cortisol which leads to metabolic changes.
Science — Abstracts: Masuzaki et al. 294 (5549): 2166
