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Seizures / Epilepsy
Acute Valproate Administration Impairs Methionine Metabolism in Rats – (09-19-02)
James Bogash
Acute Valproate Administration Impairs Methionine Metabolism in Rats
Valproate is a drug commonly used to control seizures and has many potentially severe side effects. While many patients with seizures would probably have good results with lifestyle changes geared towards reducing seizure activity (i.e. stress reduction, high does fish oils to stabilize cellular membranes…), many patients need this medication. Here we see research beginning to elucidate the physiology behind the side effects. Unfortunately, it will be decades yet before high dose (most likely in the gram-dosage range) folic acid along with SAM-e and betaine will be standard recommendation.
Nutrition.org — Abstracts: Úbeda et al. 132 (9): 2737
