Aldehydes, Glutathione in Exhalation of Kids with Asthma Exacerbation – (03-04-03)

Aldehydes, Glutathione in Exhalation of Kids with Asthma Exacerbation.

I can follow along with the idea that oxidative stress and lowered glutathione levels are noted in children with asthma flare ups. However, the authors noted that a 5-day course of oral prednisone lowers the levels in exhaled breath. Huh? We have an appearent defect–lowered gluatathione and oxidative stress–and we fix it with steroids?? Excuse me for stating the obvious, but how about nebulized gluatathione inhaler and antioxidant therapy to address this? If your gas gauge reads low on gas, do you just tow around the car and call it fixed?

AJRCCM — Abstracts: Corradi et al. 167 (3): 395

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