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Gut Health 101

COLONISATION PROMOTES SENSITISATION AGAINST FOOD – (10-23-06)

James Bogash

Gastrointestinal Candida colonisation promotes sensitisation against food antigens by affecting the mucosal barrier in mice

While this is a mouse study, the concept is pretty readily accepted in functional medicine circles. If anyone has seen thrush growing in the back of an infants mouth and made an attempt to scrape it off would see the red, raw mucosa underneath. The same thing will happen along the entire lining of the GI tract w/ candida overgrowth.

So when you disrupt this important barrier between our environment and our internal mileue, all hell can break loose. When that barrier becomes more permeable (“leaky gut”) then compounds that are not supposed to enter our bodies get through, heading straight to the liver and creating additional work for the liver to process as well as activating the immune system via the Kuppfer cells of the liver. Again, another example of how our society’s overuse of antibiotics can contribute to chronic disease.

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