Tissue Necrosis Factor (TNF)
Cutaneous Disorders in Crohn’s Disease Respond to Infliximab – (08-13-01)
Cutaneous Disorders in Crohn’s Disease Respond to Infliximab
This article supports things I’ve said for awhile now. Many chronic autoimmune conditions may actually come from the same basic metabolic defect, and that the ultimate manifestation of a certain disease is just a branch along the changes caused by the original defect. We are now seeing a drug (infliximab, a drug that blocks TNF alpha from doing it’s job) that is having an effect of rheumatoid arthritis, Crohn’s disease and now several autoimmune skin disorders as well. Before we get too excited here that the answer has been found, remember that TNF alpha is needed for healthy immune function and cancer prevention. I am sure that the long term use of these drugs will produce higher rates of certain types of cancer. Lowering levels of TNF naturally included weight loss, maintaining insulin sensitivity and leaning towards a plant based diet. Improvement of Pyoderma Gangrenosum and Psoriasis Associated With Crohn Disease With Anti-Tumor Necrosis Factor alpha Monocl
