Autoimmunity
DISTINCT COMPOSITION OF GUT MICROBIOTA DURING PREGNANCY – (09-01-09)
Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women
When I describe current research to patients, I note that the lag time between research and clinical practice is about 2 decades. 20 yrs. The frustration I feel with this is truly beyond measure and contributes greatly to the disease burden in today’s society. Probably one of the greatest examples of the chasm between research and clinical practice is with probiotics in natural flora and the wanton destruction with antibiotics.
I had a new patient today that is dealing with multiple health concerns. Lupus, kidney failure, pancreatitis…it’s a long list. Several months ago she was put on IV antibiotics for about 2 wks. Given the strong relationship of the gut to autoimmune disorders, I consider it flat out malpractice that NONE of the specialists she has seen have recommend restoration of the destroyed flora.
In this particular study, we see that the bacterial flora present during pregnancy influences the weight of the unborn child. So, antibiotics given to the mom at any time before pregnancy without instruction in replacement of normal flora is likely a contributing factor to the rise in obesity in children. Quite a disturbing implication.
