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Environmental toxins can have their negative effects by inhibiting the methylation of DNA – (04-08-04)

James Bogash

Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal

For those of us that are not biochemists and our eyes glazed over at the title to this one–basically, environmental toxins can have their negative effects by inhibiting the methylation of DNA. Remember that methylation reactions are incredibly important and effect such a basic role in human physiology. Thus, problems with methylation can lead to problems in many organ systems.

In this study, the authors found that environmental toxins such as mercury-containing thimerosal inhibit DNA methylation. For the life of me, I cannot see how anyone in the pharmaceutical industry could have even considered the use of mercury as a preservative. I can see it now…”I need something to extend the shelf live of this vaccine so we can make a larger profit on vaccines given to infants. Hey–how about that potent neurotoxin mercury?”

Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal.

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