Diabetes (Type 2)
GLUCOSE LEVELS IN BLOODSTREAM CAN IRREVERSIBLY DAMAGE PROTEINS – (10-13-04)
High Levels of Dietary Advanced Glycation End Products Transform Low-Density Lipoprotein Into a Potent Redox-Sensitive Mitogen-Activated Protein Kinase Stimulant in Diabetic Patients
Okay, so maybe I’m on a kick for long titles detailing biochemistry for this Update… Actually, I couldn’t figure out how to shorten the title. When elevated glucose levels are present in the bloodstream they can irreversibly damage protein. Muscle, heart, heme…any protein. This is the idea behind checking hemoglobin A1C/glycosylated hemoglobin–it checks the damage occurring over the course of the 3-month lifespan of a RBC. So, it is becoming of concern that glycosylated proteins from our diet may have a negative impact on our health as well.
Circulation — Abstracts: Cai et al. 110 (3): 285 –
