Does Metformin Improve Clinical Features of Polycystic Ovary Syndrome?
This is a Cochrane Collaboration review of the medical literature and the bottom line is that metformin (a drug that increases insulin resistance) is an effective first line approach to anovulation in PCOS. I’m not entirely convinced that managing insulin resistance is being used clinically, however, and the birth control pill is still a common treatment (which, ironically, worsens insulin resistance…). As for these findings, I of course would advocate first using lifestyle changes and functional medicine approaches such as dietary changes, exercise and supplementation such as chromium or CLA.
Cochrane for Clinicains: Putting Evidence into Practice – December 1, 2003 – American Family Physician.
