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Heart Disease

Inhibition of hepatocyte apoB secretion by naringenin – (09-19-02)

James Bogash

Inhibition of hepatocyte apoB secretion by naringenin

Recall that naringenin is a bioflavanoid found in grapefruit and is well known to inhibit cytochrome P450 action–thus leading to potentially dangerous interactions with blood thinners. Here we see an apoB (protein carrier of lipids known to be associated with CVD risk) lowering effect of this same substance.

J. Lipid Res. — Abstracts: Borradaile et al. 43 (9): 1544

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