NSAIDs as a Trigger of Clinical Heart Failure.
NSAIDs double the risk of heart failure in patients with a history of heart problems. Considering their widespread use, the number of patients affected by this association is probably close to staggering. All by themselves, NSAIDs are believed to cause some 16-19,000 deaths per year via GI bleeding (kind of beats 20 over a lifetime, huh?).
