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Breast Cancer

Pharmacological and endogenous progestins induce vascular endothelial growth factor expression in human breast cancer cells – (06-14-01)

James Bogash

Pharmacological and endogenous progestins induce vascular endothelial growth factor expression in human breast cancer cells

I left the long title for a reason here. At first glance, this article appears to suggest that progesterone produced by the body may increase breast cancer risk. Reading into the article itself arises some very, very important issues. These are related to nomenclature. Progestins are synthetic hormones that have been altered in order to create a patent on the substance. They mimic progesterone but THEY ARE NOT PROGESTERONE. They have been mutated and the body knows the difference. This article does NOT use progesterone–the authors used progestins and then extrapolated the results over to natural progesterone–a very dangerous and unforgivable error. It would be interesting to see if natural progesterone actually did have the same effects. I believe it would not.

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