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Diabetes (Type 2)
REACTIVE OXYGEN SPECIES ASSOCIATED WITH DIABETIC DAMAGES – (02-17-03)
James Bogash
Are Oxidative Stress-Activated Signaling Pathways Mediators of Insulin Resistance and ß-Cell Dysfunction?
This article finds that reactive oxygen species (i.e. free radicals) are a result of elevated glucose levels, and these ROS than damage DNA, proteins and lipids. This damage than starts a snowball effect killing off beta cells of the pancreas and leading to the damage we associate with diabetes. This would suggest that antioxidant supplementation (N-acetylcysteine, Vit E, Vit C, CoQ10…) would be important nutrients for any patient with impaired glucose tolerance or diabetes.
Diabetes — Abstracts: Evans et al. 52 (1): 1
