Thiazolidinediones for type 2 diabetes
This is a nice review of PPAR-gamma ligands and how they work in diabetes. Two things about this article. First, you need to know that conjugated linoleic acid also acts as a PPAR gamma ligand without the side effects and has shown benefit in treating diabetes. Second, look at the withdrawal dates in the US of troglitazone vs the UK. It was almost three years later that the US pulled availability. This once again shows that you can’t always rely on the FDA to protect you. It’s a personal choice.
