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Arthritis
(TNF-) Plays a Protective Role in Acute Viral Myocarditis in Mice – (02-12-01)
James Bogash
(TNF-) Plays a Protective Role in Acute Viral Myocarditis in Mice
Careful with this!! TNF-alpha receptor blockers are the hot new class of drugs used to treat rheumatoid arthritis and now Crohn’s disease. I always worry about blocking the action of a cytokine as important as TNF-alpha–we can’t possibly begin to guess the long term effects of this suppression of the immune system. Well, maybe we can–could fatal cardiac infections be one of those long term potential side effects? Only time will tell; time and the post-marketing surveys done on the guinea pig patients…
Circulation — Abstracts: Wada et al. 103 (5): 743
