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Colon / Colorectal Cancer
Vitamin D Receptor As an Intestinal Bile Acid Sensor – (05-23-02)
James Bogash
Vitamin D Receptor As an Intestinal Bile Acid Sensor
This article suggests a mechanism for the observed effects of Vit D lowering risk of colon cancer. Vit D upregulates production of an enzyme system needing to detoxify lithocholic acid, a bile acid with hepatoxic and carcinogenic properties. I just hope the milk people don’t get ahold of this one…we’ll never hear the end of it…
Science — Abstracts: Makishima et al. 296 (5571): 1313
